scholarly journals Adjuvant chemotherapy combination of vinblastine, actinomycin D, bleomycin, and chlorambucil following retroperitoneal lymph node dissection for stage II testis tumor

Cancer ◽  
1981 ◽  
Vol 47 (5) ◽  
pp. 840-844 ◽  
Author(s):  
Davor Vugrin ◽  
Willet F. Whitmore ◽  
Esteban Cvitkovic ◽  
Harry Grabstald ◽  
Pramod Sogani ◽  
...  
1983 ◽  
Vol 1 (3) ◽  
pp. 171-178 ◽  
Author(s):  
N J Vogelzang ◽  
E E Fraley ◽  
P H Lange ◽  
J Torkelson ◽  
S Levitt ◽  
...  

Between 1970 and 1980, 82 patients with pathologic stage II nonseminomatous germ cell testicular carcinoma were treated at the University of Minnesota. Of the 30 patients treated with a retroperitoneal lymph node dissection, 22 (77%) relapsed. Of the 18 patients treated with retroperitoneal lymph node dissection and adjuvant radiotherapy, 12 (63%) relapsed. Sixteen patients received adjuvant chemotherapy before 1976, and 14 (87.5%) relapsed. After 1976, 18 patients received adjuvant chemotherapy (11 with cisplatin) and 2 (11%) have relapsed. No patient treated with cisplatin-based adjuvant chemotherapy has relapsed. The toxicity has been modest. Cisplatin-based chemotherapy is an effective and a safe adjuvant therapy for stage II nonseminomatous germ cell testicular carcinoma.


2007 ◽  
Vol 177 (4S) ◽  
pp. 331-331 ◽  
Author(s):  
Octavio Castillo ◽  
Jose M. Campero ◽  
Rafael Sánchez-Salas ◽  
Fernando P. Secin ◽  
Gonzalo Vitagliano ◽  
...  

2011 ◽  
Vol 9 (4) ◽  
pp. 527-529 ◽  
Author(s):  
Eulalio Damazio ◽  
Eliana Caran ◽  
Valdemar Ortiz ◽  
Antonio Macedo Junior

ABSTRACT We report on a 16-year-old male with paratesticular rhabdomyosarcoma who underwent retroperitoneal lymph node dissection due to a stage I tumor (normal retroperitoneal computed tomoghaphy). The surgical finding was three enlarged nodes, positive for metastatic disease. Patient was referred to adjuvant chemotherapy. This case suggests that the Intergroup Rhabdomyosarcoma Study Group IV protocol is subject to questions regarding adolescents with paratesticular rhabdomyosarcoma, and that negative retroperitoneal CT does not preclude the need of lymph node dissection.


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